Metabolic retroconversion of trimethylamine N-oxide and the gut microbiota
Abstract Background The dietary methylamines choline, carnitine, and phosphatidylcholine are used by the gut microbiota to produce a range of metabolites, including trimethylamine (TMA).However, little is known about the use of trimethylamine N-oxide (TMAO) by this consortium of microbes.Results A feeding study using deuterated TMAO in C57BL6/J mic